The ProteomeXchange consortium in 2020: enabling ‘big data’ approaches in proteomics

The ProteomeXchange (PX) consortium of proteomics resources (http://www.proteomexchange.org) has standardized data submission and dissemination of mass spectrometry proteomics data worldwide since 2012. In this paper, we describe the main developments since the previous update manuscript was published in Nucleic Acids Research in 2017. Since then, in addition to the four PX existing members at the time (PRIDE, PeptideAtlas including the PASSEL resource, MassIVE and jPOST), two new resources have joined PX: iProX (China) and Panorama Public (USA). We first describe the updated submission guidelines, now expanded to include six members. Next, with current data submission statistics, we demonstrate that the…

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  National Science Foundation

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  National Sleep Foundation

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  Wellcome

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  University of Washington

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  Ministry of Science and Technology of the People's Republic of China

  Awards: 2016YFC0901701, 2016YFB0201702
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  National Institutes of Health

  Awards: U54EB020406, U01DK121289, R01 GM121696, R24 GM127667-01, 5P41GM103484-07, U54 HG008097, R01 GM103551, R01GM087221, R24GM127667
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  Biotechnology and Biological Sciences Research Council

  Awards: BB/P024599/1, BB/N022432/1, BB/N022432/1, BB/N022440/1, BB/P024599/1, BB/N022440/1
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  National Institute on Aging

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  National Bioscience Database Center

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