Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study

Attal, Michel; Richardson, Paul G.; Rajkumar, S. Vincent; Miguel, Jesús F. San; Beksaç, Meral; Špıčka, Ivan; Leleu, Xavier; Schjesvold, Fredrik; Moreau, Philippe; Dimopoulos, Meletios Α.; Huang, Jeffrey Shang-Yi; Minařík, Jiří; Cavo, Michèle; Prince, H. Miles; Macé, Sandrine; Corzo, Kathryn P.; Campana, Frank; Le-Guennec, Solenn; Dubin, Franck; Anderson, Kenneth C.; Attal, Michel; Richardson, Paul G.; Rajkumar, S. Vincent; Miguel, Jesús F. San; Beksaç, Meral; Špıčka, Ivan; Leleu, Xavier; Schjesvold, Fredrik; Moreau, Philippe; Dimopoulos, Meletios Α.; Huang, Jeffrey Shang-Yi; Minařík, Jiří; Cavo, Michèle; Prince, H. Miles; Macé, Sandrine; Corzo, Kathryn P.; Campana, Frank; Le-Guennec, Solenn; Dubin, Franck; Anderson, Kenneth C.; Harrison, Simon J.; Janowski, Wojciech; Kerridge, Ian; Spencer, Andrew; Delforge, Michel; Fostier, Karel; Vlummens, Philip; Wu, Ka Lung; LeBlanc, Richard; Pavic, Michel; Sébag, Michaël; Hájek, Roman; Maisnar, Vladimír; Pour, Luděk; Gregersen, Henrik; Benbouker, Lotfi; Caillot, Denis; Escoffre‐Barbe, Martine; Façon, Thierry; Frenzel, Laurent; Hulin, Cyrille; Karlin, Lionel; Kolb, Brigitte; Pegourié, Brigitte; Perrot, Aurore; Tiab, Mourad; Vincent, Laure; Niederwieser, Dietger; Anagnostopoulos, Αchilles; Delimpasi, Sosana; Kyrtsonis, Marie‐Christine; Symeonidis, Anargyros; Illés, Árpád; Mikala, Gábor; Nagy, Zsolt; Bringen, Sara; Corradini, Paolo; Ciceri, Fabio; Lemoli, Roberto M.; Liberati, Anna Marina; Nozzoli, Chiara; Zambello, Renato; Iida, Shinsuke; Ikeda, Takashi; Iyama, Satoshi; Matsumoto, Morio; Shimazaki, Chihiro; Sunami, Kazutaka; Suzuki, Kenshi; Uchiyama, Michihiro; Koh, Youngil; Kım, Kihyun; Lee, Jae Hoon; Min, Chang‐Ki; Blacklock, Hillary; Goodman, Hugh J. B.; Neylon, Annette; Simpson, David; Grosicki, Sebastian; Jurczyszyn, Artur; Walter‐Croneck, Adam; Warzocha, Krzysztof; Araújo, Luís Francisco; Moreira, Cláudia; Doronin, Vadim; Менделеева, Л. П.; Vorobyev, Vladimir; Vranovský, Andrej; Alegre, Adrían; Gironella, Mercedes; Perez, Marta Sonia Gonzalez; Montes, Carmen; Ocio, Enrique M.; Rodríguez, Paula; Hardling, Mats; Lauri, Birgitta; Wang, Ming‐Chung; Yeh, Su‐Peng; Arat, Mutlu; Demırkan, Fatih; Gülbaş, Zafer; Beşışık, Sevgi Kalayoğlu; Karadoǧan, Ìhsan; Tuğlular, Tülin; Ünal, Ali; Vural, Filiz; Sive, Jonathan; Streetly, Matthew; Yong, Kwee; Tache, Jason

doi:10.1016/s0140-6736(19)32556-5

articleThe LancetNov 14, 2019Closed access

Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study

MAMichel Attal PGPaul G. Richardson SVS. Vincent Rajkumar JFJesús F. San Miguel MBMeral Beksaç

Institut universitaire du cancer de Toulouse Oncopole · Harvard University · +20 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

634

total citations

FWCI: 59.14
Percentile: 100%
References: 34

Citations per year

Authors

130

MA
Michel AttalCorresponding
Institut universitaire du cancer de Toulouse Oncopole
PG
Paul G. RichardsonCorresponding
Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center
SV
S. Vincent Rajkumar
Mayo Clinic in Arizona
JF
Jesús F. San Miguel
Clinica Universidad de Navarra, Centro de Investigación Biomédica en Red de Cáncer
MB
Meral Beksaç
Ankara University

Topics & keywords

Topics

Multiple Myeloma Research and Treatments99%
Ubiquitin and proteasome pathways0%
Cancer Immunotherapy and Biomarkers0%

Keywords

Pomalidomide
Dexamethasone
Medicine
Multiple myeloma
Lenalidomide
Internal medicine
Refractory (planetary science)
Oncology

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Funding

SP
Sanofi Pasteur