A population-based study of cardiovascular disease mortality risk in US cancer patients

AIMS: This observational study characterized cardiovascular disease (CVD) mortality risk for multiple cancer sites, with respect to the following: (i) continuous calendar year, (ii) age at diagnosis, and (iii) follow-up time after diagnosis. METHODS AND RESULTS: The Surveillance, Epidemiology, and End Results program was used to compare the US general population to 3 234 256 US cancer survivors (1973-2012). Standardized mortality ratios (SMRs) were calculated using coded cause of death from CVDs (heart disease, hypertension, cerebrovascular disease, atherosclerosis, and aortic aneurysm/dissection). Analyses were adjusted by age, race, and sex. Among 28 cancer types, 1 228 328 patients (38.0%) died from cancer…

• AC
  American Cancer Society

  Awards: MSRG-18-136-01-CPPB, LRP 1 L30 CA231572-01
• NC
  National Center for Advancing Translational Sciences

  Awards: 5 UL1 TR002014, TR002014, UL1 TR002014, KL2 TR002015, TR002015