reviewInternational Journal of Molecular SciencesNov 28, 2019GOLD OA

Cytokines in Inflammatory Disease

Universität Hamburg · University Medical Center Hamburg-Eppendorf · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this review, we focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the…

Citation impact

1,916
total citations
FWCI
63.94
Percentile
100%
References
273
Citations per year

Authors

3

Topics & keywords

Keywords
  • Disease
  • Tumor necrosis factor alpha
  • Immunology
  • Proinflammatory cytokine
  • Inflammation
  • Immune system
  • Medicine
  • Interleukin
UN Sustainable Development Goals
  • Good health and well-being
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