Improved metagenomic analysis with Kraken 2
Johns Hopkins University · Johns Hopkins Medicine
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Abstract
Although Kraken's k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.
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6,974
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3Topics & keywords
Topics
Keywords
- Metagenomics
- Biology
- Limiting
- Computational biology
- Genetics
- Gene
- Engineering
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