articleAccounts of Chemical ResearchNov 27, 2019Closed access

Chemistry with Electrochemically Generated N-Centered Radicals

Xiamen University · Collaborative Innovation Center of Chemistry for Energy Materials

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Abstract

Evolution without the need for chemical oxidants. In addition, cathodic solvent reduction can continuously generate a low concentration of base, which facilitates anodic substrate oxidation. Such a mechanistic paradigm obviates the need for stoichiometric strong bases and avoids base-promoted decomposition of sensitive substrates or products. Furthermore, electrode materials can also be adjusted to control the reaction outcome, as demonstrated by the synthesis of N-heteroaromatics and the corresponding N-oxides from biaryl ketoximes.

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1,035
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55.15
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100%
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Authors

2

Topics & keywords

Keywords
  • Chemistry
  • Radical
  • Electrosynthesis
  • Electrochemistry
  • Electrophile
  • Radical ion
  • Hydrogen atom abstraction
  • Radical substitution
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