CDD/SPARCLE: the conserved domain database in 2020
National Institutes of Health · National Center for Biotechnology Information
Abstract
As NLM's Conserved Domain Database (CDD) enters its 20th year of operations as a publicly available resource, CDD curation staff continues to develop hierarchical classifications of widely distributed protein domain families, and to record conserved sites associated with molecular function, so that they can be mapped onto user queries in support of hypothesis-driven biomolecular research. CDD offers both an archive of pre-computed domain annotations as well as live search services for both single protein or nucleotide queries and larger sets of protein query sequences. CDD staff has continued to characterize protein families via conserved domain architectures and has built up a significant corpus of curated…
Citation impact
- FWCI
- 138.93
- Percentile
- 100%
- References
- 11
Authors
17- SLShennan Lu
National Institutes of Health, National Center for Biotechnology Information
- JWJiyao Wang
National Institutes of Health, National Center for Biotechnology Information
- FCFarideh Chitsaz
National Institutes of Health, National Center for Biotechnology Information
- MKMyra K. Derbyshire
National Institutes of Health, National Center for Biotechnology Information
- RCRenata C. Geer
National Institutes of Health, National Center for Biotechnology Information
Topics & keywords
- RefSeq
- Biology
- Domain (mathematical analysis)
- Protein domain
- Architecture domain
- Conserved sequence
- Function (biology)
- Computational biology