reviewChemical Society ReviewsNov 21, 2019Closed access

Synthetic ratiometric fluorescent probes for detection of ions

Yonsei University · Government of the Republic of Korea · +3 more institutions

PubMed
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Abstract

Metal cations and anions are essential for versatile physiological processes. Dysregulation of specific ion levels in living organisms is known to have an adverse effect on normal biological events. Owing to the pathophysiological significance of ions, sensitive and selective methods to detect these species in biological systems are in high demand. Because they can be used in methods for precise and quantitative analysis of ions, organic dye-based ratiometric fluorescent probes have been extensively explored in recent years. In this review, recent advances (2015-2019) made in the development and biological applications of synthetic ratiometric fluorescent probes are described. Particular emphasis is given to…

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