Spheroid Culture System Methods and Applications for Mesenchymal Stem Cells

Owing to the importance of stem cell culture systems in clinical applications, researchers have extensively studied them to optimize the culture conditions and increase efficiency of cell culture. A spheroid culture system provides a similar physicochemical environment in vivo by facilitating cell-cell and cell-matrix interaction to overcome the limitations of traditional monolayer cell culture. In suspension culture, aggregates of adjacent cells form a spheroid shape having wide utility in tumor and cancer research, therapeutic transplantation, drug screening, and clinical study, as well as organic culture. There are various spheroid culture methods such as hanging drop, gel embedding, magnetic levitation,…

• CU
  Chung-Ang University
• KH
  Korea Health Industry Development Institute

  Award: HI16C0106
• CF
  Centers for Disease Control and Prevention
• KC
  Korea Centers for Disease Control and Prevention

  Award: 2018ER610300