A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Science for Life Laboratory · Novo Nordisk Foundation · +6 more institutions
Abstract
Blood is the predominant source for molecular analyses in humans, both in clinical and research settings. It is the target for many therapeutic strategies, emphasizing the need for comprehensive molecular maps of the cells constituting human blood. In this study, we performed a genome-wide transcriptomic analysis of protein-coding genes in sorted blood immune cell populations to characterize the expression levels of each individual gene across the blood cell types. All data are presented in an interactive, open-access Blood Atlas as part of the Human Protein Atlas and are integrated with expression profiles across all major tissues to provide spatial classification of all protein-coding genes. This allows for…
Citation impact
- FWCI
- 19.94
- Percentile
- 100%
- References
- 63
Authors
23- MUMathias UhlénCorresponding
Science for Life Laboratory, Novo Nordisk Foundation, Karolinska Institutet, KTH Royal Institute of Technology, Technical University of Denmark
- MKMax Karlsson
Science for Life Laboratory, KTH Royal Institute of Technology
- WZWen Zhong
Science for Life Laboratory, KTH Royal Institute of Technology
- ATAbdellah Tebani
Science for Life Laboratory, KTH Royal Institute of Technology
- CPChristian Pou
Science for Life Laboratory, Karolinska Institutet
Topics & keywords
- Transcriptome
- Gene
- Genome
- Human genome
- Biology
- Computational biology
- Genetics
- Gene expression