The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer
City University of Hong Kong · Kowloon Hospital · +9 more institutions
Abstract
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
Citation impact
- FWCI
- 33.40
- Percentile
- 100%
- References
- 54
Authors
6- PLPui‐Chi Lo
City University of Hong Kong, Kowloon Hospital
- MSM. Salomé Rodríguez‐Morgade
Instituto de Investigaciones Químicas, Universidad Autónoma de Madrid
- RKRavindra K. PandeyCorresponding
Roswell Park Comprehensive Cancer Center, Dynamic Research (United States), Buffalo BioLabs
- DKDennis K. P. NgCorresponding
Chinese University of Hong Kong
- TTTomás Torres⊗Corresponding
Madrid Institute for Advanced Studies, Instituto de Investigaciones Químicas, Universidad Autónoma de Madrid
Topics & keywords
- Photodynamic therapy
- Cancer
- Phthalocyanine
- Cancer therapy
- Chemistry
- Medicine
- Cancer research
- Nanotechnology