Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
Jilin University · Union Hospital · +17 more institutions
Abstract
DAMP, damage-associated molecular pattern; PBMCMs, peripheral blood mononuclear cell-derived macrophages; PDAC, pancreatic ductal adenocarcinoma; s.c., subcutaneously; TAMs, tumor-associated macrophages; TME, tumor microenvironment.
Citation impact
- FWCI
- 42.44
- Percentile
- 100%
- References
- 94
Authors
10- EDEnyong Dai
Jilin University, Union Hospital
- LHLeng Han
Jilin University, Union Hospital
- JLJiao Liu
Third Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University
- YXYangchun Xie
Central South University, Second Xiangya Hospital of Central South University
- GKGuido Kroemer
Karolinska University Hospital, Inserm, Chinese Academy of Sciences, Institut Gustave Roussy, Sorbonne Université, Centre de Recherche des Cordeliers, Hôpital Européen Georges-Pompidou, Hôpital Européen, Suzhou Institute of Systems Medicine
Topics & keywords
- KRAS
- Biology
- Autophagy
- Cancer research
- Macrophage polarization
- Oncogene
- Extracellular
- Mutation