Gasdermin E–mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome
Chinese Academy of Medical Sciences & Peking Union Medical College · Henan Cancer Hospital · +6 more institutions
Indexed incrossrefpubmed
Abstract
GSDME-mediated target cell pyroptosis by CAR T cells activates macrophages to release proinflammatory cytokines for CRS.
Citation impact
540
total citations
- FWCI
- 27.27
- Percentile
- 100%
- References
- 46
Citations per year
Authors
20- YLYuying LiuCorresponding
Chinese Academy of Medical Sciences & Peking Union Medical College
- YFYiliang FangCorresponding
Chinese Academy of Medical Sciences & Peking Union Medical College
- XCXinfeng ChenCorresponding
Henan Cancer Hospital, First Affiliated Hospital of Zhengzhou University
- ZWZhenfeng Wang
Chinese Academy of Medical Sciences & Peking Union Medical College
- XLXiaoyu Liang
Chinese Academy of Medical Sciences & Peking Union Medical College
Topics & keywords
Topics
Keywords
- Pyroptosis
- Granzyme B
- Cell biology
- Cytotoxic T cell
- Cytokine
- CD8
- Granzyme
- Cell
No related works found for this paper.