articleJournal of Medical VirologyJan 22, 2020BRONZE OA

Cross‐species transmission of the newly identified coronavirus 2019‐nCoV

Peking University · The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine · +6 more institutions

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Abstract

The current outbreak of viral pneumonia in the city of Wuhan, China, was caused by a novel coronavirus designated 2019-nCoV by the World Health Organization, as determined by sequencing the viral RNA genome. Many initial patients were exposed to wildlife animals at the Huanan seafood wholesale market, where poultry, snake, bats, and other farm animals were also sold. To investigate possible virus reservoir, we have carried out comprehensive sequence analysis and comparison in conjunction with relative synonymous codon usage (RSCU) bias among different animal species based on the 2019-nCoV sequence. Results obtained from our analyses suggest that the 2019-nCoV may appear to be a recombinant virus between the…

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