articlePure Amsterdam UMCSep 1, 2020GREEN OA

Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis

Abstract

Researchers increasingly use meta-analysis to synthesize the results of several studies in order to estimate a common effect. When the outcome variable is continuous, standard meta-analytic approaches assume that the primary studies report the sample mean and standard deviation of the outcome. However, when the outcome is skewed, authors sometimes summarize the data by reporting the sample median and one or both of (i) the minimum and maximum values and (ii) the first and third quartiles, but do not report the mean or standard deviation. To include these studies in meta-analysis, several methods have been developed to estimate the sample mean and standard deviation from the reported summary data. A major…

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Topics & keywords

Topics
Keywords
  • Standard deviation
  • Statistics
  • Quartile
  • Quantile
  • Standard error
  • Sample size determination
  • Sample mean and sample covariance
  • Meta-analysis
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