Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement
Cedars-Sinai Medical Center · Cardiovascular Institute of the South · +25 more institutions
Abstract
There are scant data on long-term clinical outcomes and bioprosthetic-valve function after transcatheter aortic-valve replacement (TAVR) as compared with surgical aortic-valve replacement in patients with severe aortic stenosis and intermediate surgical risk.
We enrolled 2032 intermediate-risk patients with severe, symptomatic aortic stenosis at 57 centers. Patients were stratified according to intended transfemoral or transthoracic access (76.3% and 23.7%, respectively) and were randomly assigned to undergo either TAVR or surgical replacement. Clinical, echocardiographic, and health-status outcomes were followed for 5 years. The primary end point was death from any cause or disabling stroke.
Citation impact
- FWCI
- 79.72
- Percentile
- 100%
- References
- 31
Authors
34- RMRaj MakkarCorresponding
Cedars-Sinai Medical Center, Cardiovascular Institute of the South
- VHVinod H. Thourani
Cardiovascular Institute of the South, Piedmont Atlanta Hospital
- MJMichael J. Mack
Cardiovascular Institute of the South, Baylor Scott & White Health
- SKSusheel Kodali
NewYork–Presbyterian Hospital, Cardiovascular Institute of the South, Columbia University Irving Medical Center, New York Hospital Queens
- SKSamir Kapadia
Cleveland Clinic, Cardiovascular Institute of the South
Topics & keywords
- Medicine
- Valve replacement
- Hazard ratio
- Stenosis
- Stroke (engine)
- Aortic valve replacement
- Cohort
- Surgery
- Good health and well-being