Recent Advances in Host–Guest Self‐Assembled Cyclodextrin Carriers: Implications for Responsive Drug Delivery and Biomedical Engineering
Ollscoil na Gaillimhe – University of Galway · National Institute of Pharmaceutical Education and Research - Ahmedabad · +2 more institutions
Abstract
Abstract This Review is an overview of the unique characteristics of cyclodextrin in forming an inclusion complex via host–guest noncovalent interactions. The modification of cyclodextrin advances its application as a pharmaceutical solubilizer, fabrication of functional molecular machines such as polyrotaxane, polypseudorotaxane, and polycatenanes and grafting of cyclodextrin with different linear, branched chain polymers. The different stimuli‐based supramolecular assemblies involving cyclodextrin as a key mediator with linked triggering responses on payload release is highlighted. In addition, the applications of cyclodextrin in diagnostic imaging and medical devices is briefly demonstrated. Cyclodextrin is…
Citation impact
- FWCI
- 30.48
- Percentile
- 100%
- References
- 147
Authors
6- JWJitendra Wankar
Ollscoil na Gaillimhe – University of Galway
- NGNiranjan G. Kotla
Ollscoil na Gaillimhe – University of Galway
- SGSonia Gera
National Institute of Pharmaceutical Education and Research - Ahmedabad, National Institute of Pharmaceutical Education and Research
- SRSwetha Rasala
Ollscoil na Gaillimhe – University of Galway
- APAbhay PanditCorresponding
Ollscoil na Gaillimhe – University of Galway
Topics & keywords
- Cyclodextrin
- Nanotechnology
- Drug delivery
- Materials science
- Supramolecular chemistry
- Biocompatible material
- Combinatorial chemistry
- Biomedical engineering