Immunotherapy for glioma: Current management and future application
Central South University · Xiangya Hospital Central South University
Abstract
Gliomas are intrinsic brain tumors that originate from neuroglial progenitor cells. Conventional therapies, including surgery, chemotherapy, and radiotherapy, have achieved limited improvements in the prognosis of glioma patients. Immunotherapy, a revolution in cancer treatment, has become a promising strategy with the ability to penetrate the blood-brain barrier since the pioneering discovery of lymphatics in the central nervous system. Here we detail the current management of gliomas and previous studies assessing different immunotherapies in gliomas, despite the fact that the associated clinical trials have not been completed yet. Moreover, several drugs that have undergone clinical trials are listed as…
Citation impact
- FWCI
- 56.96
- Percentile
- 100%
- References
- 175
Authors
5- SXShengchao Xu
Central South University, Xiangya Hospital Central South University
- LTLu Tang
Central South University, Xiangya Hospital Central South University
- XLXizhe Li
Central South University, Xiangya Hospital Central South University
- FFFan FanCorresponding
Central South University, Xiangya Hospital Central South University
- ZLZhixiong LiuCorresponding
Central South University, Xiangya Hospital Central South University
Topics & keywords
- Glioma
- Immunotherapy
- Medicine
- Clinical trial
- Radiation therapy
- Chemotherapy
- Oncology
- Cancer
- Good health and well-being