articleJournal of Medicinal ChemistryFeb 11, 2020BRONZE OA

α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

German Center for Infection Research · University of Lübeck · +5 more institutions

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Abstract

Exhibits three-digit picomolar activity against the Middle East Respiratory Syndrome coronavirus.

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606
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Authors

14

Topics & keywords

Keywords
  • Chemistry
  • Replication (statistics)
  • Coronavirus
  • Virology
  • Broad spectrum
  • Enterovirus
  • Viral replication
  • 2019-20 coronavirus outbreak
UN Sustainable Development Goals
  • Good health and well-being
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