Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studies
Norwegian University of Science and Technology · Oslo Nye Høyskole · +7 more institutions
Abstract
BACKGROUND AND AIM: Epidemiological studies have reported increased risk of cardiovascular disease, cancer and all-cause mortality with greater resting heart rate, however, the evidence is not consistent. Differences by gender, adjustment for confounding factors, as well as the potential impact of subclinical disease are not clear. A previous meta-analysis missed a large number of studies, and data for atrial fibrillation have not been summarized before. We therefore aimed to clarify these associations in a systematic review and meta-analysis of prospective studies. METHODS AND RESULTS: = 94.0%, n = 48) for all-cause mortality. There was a positive dose-response relationship for all outcomes except for atrial…
Citation impact
- FWCI
- 89.13
- Percentile
- 100%
- References
- 331
Authors
10- DADagfinn AuneCorresponding
Norwegian University of Science and Technology, Oslo Nye Høyskole, Imperial College London
- ELEdward L. Giovannucci
Brigham and Women's Hospital, Harvard University
- PBPaolo Boffetta
Icahn School of Medicine at Mount Sinai
- LTLars Thore Fadnes
University of Bergen
- NKNaNa Keum
Harvard University
Topics & keywords
- Meta-analysis
- Medicine
- Disease
- Cancer
- Prospective cohort study
- Environmental health
- Cause of death
- Systematic review
- Good health and well-being