reviewJournal of Pharmaceutical AnalysisMar 1, 2020GOLD OA

Recent advances and perspectives of nucleic acid detection for coronavirus

Zhejiang University

PubMed
Indexed incrossrefdoajpubmed

Abstract

The recent pneumonia outbreak caused by a novel coronavirus (SARS-CoV-2) is posing a great threat to global public health. Therefore, rapid and accurate identification of pathogenic viruses plays a vital role in selecting appropriate treatments, saving people's lives and preventing epidemics. It is important to establish a quick standard diagnostic test for the detection of the infectious disease (COVID-19) to prevent subsequent secondary spread. Polymerase chain reaction (PCR) is regarded as a gold standard test for the molecular diagnosis of viral and bacterial infections with high sensitivity and specificity. Isothermal nucleic acid amplification is considered to be a highly promising candidate method due…

Citation impact

532
total citations
FWCI
11.88
Percentile
100%
References
48
Citations per year

Authors

7

Topics & keywords

Keywords
  • Loop-mediated isothermal amplification
  • Coronavirus
  • Nucleic acid
  • Nucleic acid detection
  • Coronavirus disease 2019 (COVID-19)
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Gold standard (test)
  • Outbreak
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.

Funding