Lipids and Alzheimer’s Disease

Lipids, as the basic component of cell membranes, play an important role in human health as well as brain function. The brain is highly enriched in lipids, and disruption of lipid homeostasis is related to neurologic disorders as well as neurodegenerative diseases such as Alzheimer's disease (AD). Aging is associated with changes in lipid composition. Alterations of fatty acids at the level of lipid rafts and cerebral lipid peroxidation were found in the early stage of AD. Genetic and environmental factors such as apolipoprotein and lipid transporter carrying status and dietary lipid content are associated with AD. Insight into the connection between lipids and AD is crucial to unraveling the metabolic aspects…

• MO
  Ministry of Science and Technology, Taiwan

  Awards: MOST-106-2628-B-006-001-MY4, MOST-105-2628-B-006-016-MY3, MOST-105-2628-B-006-016-MY3 and MOST-106-2628-B-006-001-MY4
• NC
  National Cheng Kung University