reviewJournal of Medical VirologyFeb 27, 2020BRONZE OA

The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients

First Bethune Hospital of Jilin University · China Academy of Chinese Medical Sciences · +1 more institution

PubMed
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Abstract

Following the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), another highly pathogenic coronavirus named SARS-CoV-2 (previously known as 2019-nCoV) emerged in December 2019 in Wuhan, China, and rapidly spreads around the world. This virus shares highly homological sequence with SARS-CoV, and causes acute, highly lethal pneumonia coronavirus disease 2019 (COVID-19) with clinical symptoms similar to those reported for SARS-CoV and MERS-CoV. The most characteristic symptom of patients with COVID-19 is respiratory distress, and most of the patients admitted to the intensive care could not breathe spontaneously. Additionally, some patients with…

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2,343
total citations
FWCI
193.90
Percentile
100%
References
56
Citations per year

Authors

3

Topics & keywords

Keywords
  • Coronavirus
  • Medicine
  • Respiratory system
  • Respiratory failure
  • Severe acute respiratory syndrome
  • Pneumonia
  • Virology
  • Betacoronavirus
UN Sustainable Development Goals
  • Good health and well-being
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