Linking Structure and Function in Macroscale Brain Networks
Montreal Neurological Institute and Hospital · McGill University · +1 more institution
Abstract
Structure-function relationships are a fundamental principle of many naturally occurring systems. However, network neuroscience research suggests that there is an imperfect link between structural connectivity and functional connectivity in the brain. Here, we synthesize the current state of knowledge linking structure and function in macroscale brain networks and discuss the different types of models used to assess this relationship. We argue that current models do not include the requisite biological detail to completely predict function. Structural network reconstructions enriched with local molecular and cellular metadata, in concert with more nuanced representations of functions and properties, hold great…
Citation impact
- FWCI
- 55.49
- Percentile
- 100%
- References
- 154
Authors
4- LELaura E. Suárez
Montreal Neurological Institute and Hospital, McGill University
- RDRoss D. Markello
Montreal Neurological Institute and Hospital, McGill University
- RFRichard F. Betzel
Indiana University Bloomington
- BMBratislav MišićCorresponding
Montreal Neurological Institute and Hospital, McGill University
Topics & keywords
- Psychology
- Brain function
- Cognitive science
- Neuroscience
- Function (biology)
- Brain Structure and Function
- Cognition
- Evolutionary biology