reviewJournal of the American College of CardiologyFeb 24, 2020HYBRID OA

Biological Versus Chronological Aging

MRMagda R. HamczykRMRosa M. NevadoABAna BarettinoVFValentı́n FusterVAVicente Andrés

Centro de Investigación Biomédica en Red · Centro de Investigación en Red en Enfermedades Cardiovasculares · +4 more institutions

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Abstract

Aging is the main risk factor for vascular disease and ensuing cardiovascular and cerebrovascular events, the leading causes of death worldwide. In a progressively aging population, it is essential to develop early-life biomarkers that efficiently identify individuals who are at high risk of developing accelerated vascular damage, with the ultimate goal of improving primary prevention and reducing the health care and socioeconomic impact of age-related cardiovascular disease. Studies in experimental models and humans have identified 9 highly interconnected hallmark processes driving mammalian aging. However, strategies to extend health span and life span require understanding of interindividual differences in…

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470
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Authors

5

Topics & keywords

Topics
Keywords
  • Medicine
  • Disease
  • Biological age
  • Population ageing
  • Life span
  • Gerontology
  • Psychological intervention
  • Ageing
UN Sustainable Development Goals
  • Good health and well-being
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