Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes

In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tract and then induced pneumonia, thus molecular diagnosis based on oral swabs was used for confirmation of this disease. Likewise, patient will be released upon two times of negative detection from oral swabs. However, many coronaviruses can also be transmitted through oral-fecal route by infecting intestines. Whether 2019-nCoV infected patients also carry virus in other organs like intestine need to be tested. We conducted investigation on patients in a local hospital who were infected with this virus. We found…

• NC
  National Children's Research Centre
• DM
  Duke-NUS Medical School
• NN
  National Natural Science Foundation of China

  Award: 81822028
• MO
  Ministry of Science and Technology of the People's Republic of China

  Award: 2018ZX10305409-004-001
• YI
  Youth Innovation Promotion Association of the Chinese Academy of Sciences

  Award: 2019328
• YI
  Youth Innovation Promotion Association