letterClinical Infectious DiseasesFeb 25, 2020BRONZE OA

Genomic Diversity of Severe Acute Respiratory Syndrome–Coronavirus 2 in Patients With Coronavirus Disease 2019

Chinese Academy of Sciences · Beijing Institute of Genomics · +10 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Background

A novel coronavirus (CoV), severe acute respiratory syndrome (SARS)-CoV-2, has infected >75 000 individuals and spread to >20 countries. It is still unclear how fast the virus evolved and how it interacts with other microorganisms in the lung.

Methods

We have conducted metatranscriptome sequencing for bronchoalveolar lavage fluid samples from 8 patients with SARS-CoV-2, and also analyzed data from 25 patients with community-acquired pneumonia (CAP), and 20 healthy controls for comparison.

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Funding