Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States
Synergy America (United States) · Oak Ridge Associated Universities · +3 more institutions
Abstract
The etiologic agent of an outbreak of pneumonia in Wuhan, China, was identified as severe acute respiratory syndrome coronavirus 2 in January 2020. A patient in the United States was given a diagnosis of infection with this virus by the state of Washington and the US Centers for Disease Control and Prevention on January 20, 2020. We isolated virus from nasopharyngeal and oropharyngeal specimens from this patient and characterized the viral sequence, replication properties, and cell culture tropism. We found that the virus replicates to high titer in Vero-CCL81 cells and Vero E6 cells in the absence of trypsin. We also deposited the virus into 2 virus repositories, making it broadly available to the public…
Citation impact
- FWCI
- 14.33
- Percentile
- 100%
- References
- 24
Authors
34- JLJennifer L. HarcourtCorresponding
Synergy America (United States)
- ATAzaibi Tamin
Oak Ridge Associated Universities, Centers for Disease Control and Prevention, Oak Ridge Institute for Science and Education, The University of Texas Medical Branch at Galveston
- XLXiaoyan Lu
Oak Ridge Institute for Science and Education, The University of Texas Medical Branch at Galveston, Centers for Disease Control and Prevention, Oak Ridge Associated Universities
- SKShifaq Kamili
The University of Texas Medical Branch at Galveston, Centers for Disease Control and Prevention, Oak Ridge Associated Universities, Oak Ridge Institute for Science and Education
- SKSenthil Kumar K. Sakthivel
Oak Ridge Associated Universities, Centers for Disease Control and Prevention, Oak Ridge Institute for Science and Education, The University of Texas Medical Branch at Galveston
Topics & keywords
- Vero cell
- Virology
- Coronavirus
- Virus
- Outbreak
- Pneumonia
- Medicine
- Viral replication
- Good health and well-being