Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and Outcomes Consortium
Brigham and Women's Hospital · Woman's Hospital · +31 more institutions
Abstract
To develop an evidence-based definition of sarcopenia that can facilitate identification of older adults at risk for clinically relevant outcomes (eg, self-reported mobility limitation, falls, fractures, and mortality), the Sarcopenia Definition and Outcomes Consortium (SDOC) crafted a set of position statements informed by a literature review and SDOC's analyses of eight epidemiologic studies, six randomized clinical trials, four cohort studies of special populations, and two nationally representative population-based studies.
Thirteen position statements related to the putative components of a sarcopenia definition, informed by the SDOC analyses and literature synthesis, were reviewed by an independent international expert panel (panel) iteratively and voted on by the panel during the Sarcopenia Position Statement Conference. Four position statements related to grip strength, three to lean mass derived from dual-energy x-ray absorptiometry (DXA), and four to gait speed; two were summary statements.
Citation impact
- FWCI
- 43.60
- Percentile
- 100%
- References
- 46
Authors
29- SBShalender BhasinCorresponding
Brigham and Women's Hospital, Woman's Hospital
- TGThomas G. Travison
Beth Israel Deaconess Medical Center, Hebrew SeniorLife
- TMTodd M. Manini
University of Florida
- SPSheena Patel
California Pacific Medical Center
- KMKarol M. Pencina
Brigham and Women's Hospital, Woman's Hospital
Topics & keywords
- Sarcopenia
- Medicine
- Grip strength
- Physical medicine and rehabilitation
- Population
- Lean body mass
- Physical therapy
- Gait
- Reduced inequalities
Funding
- UDU.S. Department of Defense
- FFFoundation for the National Institutes of HealthAwards: BHAS16SARC2, CAWT16SARC2
- UDU.S. Department of Health and Human Services
- UDU.S. Department of AgricultureAwards: 58-1950-4-003, No. 58-1950-4-003, 58‐1950‐4‐003
- MMMultiple Myeloma Research Foundation
- AAmgen
- ELEli Lilly and Company
- PPfizer
- UOUniversity of Washington
- JHJohns Hopkins University
- AJAbbott Japan
- RPRegeneron Pharmaceuticals
- CCytokinetics
- APAstellas Pharma
- SServier
- NINational Institutes of HealthAwards: BHAS16SARC2, CAWT16SARC2
- CFCenters for Disease Control and Prevention
- NINovartis Institutes for BioMedical Research
- MRMedical Research CouncilAwards: MC_UU_12011/2, MC_UU_12011/1
- NINational Institute on AgingAwards: 1UO1AG051421, 1R13AG060712‐01
- NCNational Cancer Institute
- NINational Institute of Nursing Research
- NINational Institute of Child Health and Human Development
- NCNational Center for Medical Rehabilitation Research