preprintmedRxivFeb 27, 2020GREEN OA

Comorbidity and its impact on 1,590 patients with COVID-19 in China: A Nationwide Analysis

First Affiliated Hospital of Guangzhou Medical University · State Key Laboratory of Respiratory Disease · +26 more institutions

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Abstract

Abstract Objective To evaluate the spectrum of comorbidities and its impact on the clinical outcome in patients with coronavirus disease 2019 (COVID-19). Design Retrospective case studies Setting 575 hospitals in 31 province/autonomous regions/provincial municipalities across China Participants 1,590 laboratory-confirmed hospitalized patients. Data were collected from November 21 st , 2019 to January 31 st , 2020. Main outcomes and measures Epidemiological and clinical variables (in particular, comorbidities) were extracted from medical charts. The disease severity was categorized based on the American Thoracic Society guidelines for community-acquired pneumonia. The primary endpoint was the composite…

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