reviewAdvanced Drug Delivery ReviewsJan 1, 2020HYBRID OA

An emerging focus on lipids in extracellular vesicles

Oslo University Hospital · University of Oslo

PubMed
Indexed incrossrefpubmed

Abstract

Extracellular vesicles contain a lipid bilayer membrane that protects the encapsulated material, such as proteins, nucleic acids, lipids and metabolites, from the extracellular environment. These vesicles are released from cells via different mechanisms. During recent years extracellular vesicles have been studied as possible biomarkers for different diseases, as biological nanoparticles for drug delivery, and in basic studies as a tool to understand the structure of biological membranes and the mechanisms involved in vesicular trafficking. Lipids are essential molecular components of extracellular vesicles, but at the moment our knowledge about the lipid composition and the function of lipids in these…

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541
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100%
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196
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Authors

4

Topics & keywords

Keywords
  • Vesicle
  • Extracellular vesicles
  • Microvesicles
  • Extracellular
  • Lipid bilayer
  • Extracellular vesicle
  • Chemistry
  • Cell biology
UN Sustainable Development Goals
  • Good health and well-being
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