The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status

An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health emergency of international concern. The emergence of SARS-CoV-2, since the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, marked the third introduction of a highly pathogenic and large-scale epidemic coronavirus into the human population in the twenty-first century. As of 1 March 2020, a total of 87,137…

• NN
  National Natural Science Foundation of China

  Awards: 81870019, COVID-19
• SY
  Sun Yat-sen University
• NS
  Natural Science Foundation of Guangdong Province

  Award: 2018A030313554
• EA
  European Academy of Allergy and Clinical Immunology
• MR
  Medical Research Council

  Award: COVID-19
• NM
  National Medical Research Council

  Award: NMRC/CIRG/1458/2016