reviewRedox BiologyMar 20, 2020GOLD OA

Physical activity and exercise: Strategies to manage frailty

JAJavier AnguloMEMariam El AssarAÁAlejandro Álvarez‐BustosLRLeocadio Rodríguez‐Mañas

Instituto Ramón y Cajal de Investigación Sanitaria · Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable · +3 more institutions

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Abstract

Frailty, a consequence of the interaction of the aging process and certain chronic diseases, compromises functional outcomes in the elderly and substantially increases their risk for developing disabilities and other adverse outcomes. Frailty follows from the combination of several impaired physiological mechanisms affecting multiple organs and systems. And, though frailty and sarcopenia are related, they are two different conditions. Thus, strategies to preserve or improve functional status should consider systemic function in addition to muscle conditioning. Physical activity/exercise is considered one of the main strategies to counteract frailty-related physical impairment in the elderly. Exercise reduces…

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4

Topics & keywords

Topics
Keywords
  • Myokine
  • Sarcopenia
  • Flexibility (engineering)
  • Medicine
  • Physical medicine and rehabilitation
  • Intervention (counseling)
  • Psychological intervention
  • Aerobic exercise
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