articleInternational Journal of Antimicrobial AgentsMar 12, 2020HYBRID OA

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

Centre National de la Recherche Scientifique · Aix-Marseille Université · +2 more institutions

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Abstract

Recently, a novel coronavirus (2019-nCoV), officially known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. Despite drastic containment measures, the spread of this virus is ongoing. SARS-CoV-2 is the aetiological agent of coronavirus disease 2019 (COVID-19) characterised by pulmonary infection in humans. The efforts of international health authorities have since focused on rapid diagnosis and isolation of patients as well as the search for therapies able to counter the most severe effects of the disease. In the absence of a known efficient therapy and because of the situation of a public-health emergency, it made sense to investigate the possible effect of…

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