articleScientific ReportsNov 19, 2014GOLD OA

Correction: Corrigendum: Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization

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Abstract

Nanoparticles (NPs) were widely used in drugs/probes delivery for improved disease diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application of NPs. However, few studies have been performed on the targeting mechanisms of these ligand-modified delivery systems. Additional studies are needed to understand the transport of nanoparticles in the cancer site, the interactions between nanoparticles and cancer cells, the intracellular trafficking of nanoparticles within the cancer cells and the subcellular destiny and potential toxicity. Interleukin 13 (IL-13) peptide can specifically bind IL-13Rα2, a receptor that is highly expressed on glioma cells but is expressed at low…

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1,062
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104.75
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100%
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Authors

7

Topics & keywords

Keywords
  • Internalization
  • Endocytosis
  • Glioma
  • Intracellular
  • Cancer cell
  • Receptor-mediated endocytosis
  • Cell
  • Cell biology
UN Sustainable Development Goals
  • Good health and well-being
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