Insights into Acinetobacter baumannii: A Review of Microbiological, Virulence, and Resistance Traits in a Threatening Nosocomial Pathogen
Zayed University · Lebanese International University
Abstract
Being a multidrug-resistant and an invasive pathogen, Acinetobacter baumannii is one of the major causes of nosocomial infections in the current healthcare system. It has been recognized as an agent of pneumonia, septicemia, meningitis, urinary tract and wound infections, and is associated with high mortality. Pathogenesis in A. baumannii infections is an outcome of multiple virulence factors, including porins, capsules, and cell wall lipopolysaccharide, enzymes, biofilm production, motility, and iron-acquisition systems, among others. Such virulence factors help the organism to resist stressful environmental conditions and enable development of severe infections. Parallel to increased prevalence of infections…
Citation impact
- FWCI
- 22.16
- Percentile
- 100%
- References
- 227
Authors
2Topics & keywords
- Acinetobacter baumannii
- Virulence
- Pathogen
- Antibiotic resistance
- Microbiology
- Antibiotics
- Biology
- Biofilm
- Good health and well-being