reviewAntibioticsMar 12, 2020GOLD OA

Insights into Acinetobacter baumannii: A Review of Microbiological, Virulence, and Resistance Traits in a Threatening Nosocomial Pathogen

Zayed University · Lebanese International University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Being a multidrug-resistant and an invasive pathogen, Acinetobacter baumannii is one of the major causes of nosocomial infections in the current healthcare system. It has been recognized as an agent of pneumonia, septicemia, meningitis, urinary tract and wound infections, and is associated with high mortality. Pathogenesis in A. baumannii infections is an outcome of multiple virulence factors, including porins, capsules, and cell wall lipopolysaccharide, enzymes, biofilm production, motility, and iron-acquisition systems, among others. Such virulence factors help the organism to resist stressful environmental conditions and enable development of severe infections. Parallel to increased prevalence of infections…

Citation impact

576
total citations
FWCI
22.16
Percentile
100%
References
227
Citations per year

Authors

2

Topics & keywords

Keywords
  • Acinetobacter baumannii
  • Virulence
  • Pathogen
  • Antibiotic resistance
  • Microbiology
  • Antibiotics
  • Biology
  • Biofilm
UN Sustainable Development Goals
  • Good health and well-being
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