Diabetes is a risk factor for the progression and prognosis of COVID ‐19
Zero to Three · Union Hospital · +3 more institutions
Abstract
A total of 174 consecutive patients confirmed with COVID-19 were studied. Demographic data, medical history, symptoms and signs, laboratory findings, chest computed tomography (CT) as well the treatment measures were collected and analysed.
We found that COVID-19 patients without other comorbidities but with diabetes (n = 24) were at higher risk of severe pneumonia, release of tissue injury-related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism. Furthermore, serum levels of inflammation-related biomarkers such as IL-6, C-reactive protein, serum ferritin and coagulation index, D-dimer, were significantly higher (P
Citation impact
- FWCI
- 32.71
- Percentile
- 100%
- References
- 27
Authors
14- WGWeina Guo
Zero to Three, Union Hospital, Huazhong University of Science and Technology
- MLMingyue Li
Zero to Three, Union Hospital, Huazhong University of Science and Technology
- YDYalan Dong
Zero to Three, Union Hospital, Huazhong University of Science and Technology
- HZHaifeng Zhou
Union Hospital, Huazhong University of Science and Technology
- ZZZili Zhang
Union Hospital, Huazhong University of Science and Technology
Topics & keywords
- Diabetes mellitus
- Medicine
- Coronavirus disease 2019 (COVID-19)
- Internal medicine
- Pneumonia
- Ferritin
- Inflammation
- Risk factor
- Good health and well-being