Stability issues of RT‐PCR testing of SARS‐CoV‐2 for hospitalized patients clinically diagnosed with COVID‐19
Sun Yat-sen University · Sixth Affiliated Hospital of Sun Yat-sen University · +3 more institutions
Abstract
In this study, we collected a total of 610 hospitalized patients from Wuhan between February 2, 2020, and February 17, 2020. We reported a potentially high false negative rate of real-time reverse-transcriptase polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 in the 610 hospitalized patients clinically diagnosed with COVID-19 during the 2019 outbreak. We also found that the RT-PCR results from several tests at different points were variable from the same patients during the course of diagnosis and treatment of these patients. Our results indicate that in addition to the emphasis on RT-PCR testing, clinical indicators such as computed tomography images should also be used not only for diagnosis and…
Citation impact
- FWCI
- 17.99
- Percentile
- 100%
- References
- 3
Authors
7- YLYafang Li
Sun Yat-sen University, Sixth Affiliated Hospital of Sun Yat-sen University
- LYLin Yao
Sun Yat-sen University, Sixth Affiliated Hospital of Sun Yat-sen University
- JLJiawei Li
Guangzhou Automobile Group (China)
- LCLei Chen
Sun Yat-sen University, Sixth Affiliated Hospital of Sun Yat-sen University
- YSYiyan Song
Zhongshan Hospital
Topics & keywords
- Coronavirus disease 2019 (COVID-19)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Virology
- 2019-20 coronavirus outbreak
- Medicine
- Sars virus
- Betacoronavirus
- Internal medicine
- Good health and well-being