articleJournal of Clinical InvestigationMar 27, 2020BRONZE OA

Clinical and immunological features of severe and moderate coronavirus disease 2019

State Key Laboratory of Respiratory Disease · Huazhong University of Science and Technology · +1 more institution

PubMed
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Abstract

BACKGROUNDSince December 2019, an outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, and is now becoming a global threat. We aimed to delineate and compare the immunological features of severe and moderate COVID-19.METHODSIn this retrospective study, the clinical and immunological characteristics of 21 patients (17 male and 4 female) with COVID-19 were analyzed. These patients were classified as severe (11 cases) and moderate (10 cases) according to the guidelines released by the National Health Commission of China.RESULTSThe median age of severe and moderate cases was 61.0 and 52.0 years, respectively. Common clinical…

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Authors

20

Topics & keywords

Keywords
  • Outbreak
  • Coronavirus disease 2019 (COVID-19)
  • Coronavirus
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • 2019-20 coronavirus outbreak
  • Disease
  • Betacoronavirus
  • Virology
UN Sustainable Development Goals
  • Good health and well-being
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