reviewCirculation ResearchApr 7, 2020Closed access

COVID-19 and the Heart

Cedars-Sinai Smidt Heart Institute

PubMed
Indexed incrossrefpubmed

Abstract

Infection with the severe acute respiratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm, and elevations of cardiac injury biomarkers. Here, we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.

Citation impact

713
total citations
FWCI
16.86
Percentile
100%
References
92
Citations per year

Authors

2

Topics & keywords

Keywords
  • Cytokine storm
  • Coronavirus disease 2019 (COVID-19)
  • Medicine
  • Pathophysiology
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • 2019-20 coronavirus outbreak
  • Coronavirus
  • Disease
UN Sustainable Development Goals
  • Good health and well-being
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Funding