Tocilizumab treatment in COVID‐19: A single center experience
Tongji Hospital · Huazhong University of Science and Technology
Abstract
Tocilizumab (TCZ), a monoclonal antibody against interleukin-6 (IL-6), emerged as an alternative treatment for COVID-19 patients with a risk of cytokine storms recently. In the present study, we aimed to discuss the treatment response of TCZ therapy in COVID-19 infected patients. The demographic, treatment, laboratory parameters of C-reactive protein (CRP) and IL-6 before and after TCZ therapy and clinical outcome in the 15 COVID-19 patients were retrospectively assessed. Totally 15 patients with COVID-19 were included in this study. Two of them were moderately ill, six were seriously ill and seven were critically ill. The TCZ was used in combination with methylprednisolone in eight patients. Five patients…
Citation impact
- FWCI
- 32.02
- Percentile
- 100%
- References
- 8
Authors
6- PLPan Luo
Tongji Hospital, Huazhong University of Science and Technology
- YLYi Liu
Tongji Hospital, Huazhong University of Science and Technology
- LQLin Qiu
Tongji Hospital, Huazhong University of Science and Technology
- XLXiulan Liu
Tongji Hospital, Huazhong University of Science and Technology
- DLDong LiuCorresponding
Tongji Hospital, Huazhong University of Science and Technology
Topics & keywords
- Tocilizumab
- Medicine
- Internal medicine
- Interleukin 6
- Cytokine storm
- Methylprednisolone
- Coronavirus disease 2019 (COVID-19)
- Gastroenterology
- Good health and well-being