articleJournal of Medical VirologyApr 7, 2020BRONZE OA

Tocilizumab treatment in COVID‐19: A single center experience

Tongji Hospital · Huazhong University of Science and Technology

PubMed
Indexed incrossrefpubmed

Abstract

Tocilizumab (TCZ), a monoclonal antibody against interleukin-6 (IL-6), emerged as an alternative treatment for COVID-19 patients with a risk of cytokine storms recently. In the present study, we aimed to discuss the treatment response of TCZ therapy in COVID-19 infected patients. The demographic, treatment, laboratory parameters of C-reactive protein (CRP) and IL-6 before and after TCZ therapy and clinical outcome in the 15 COVID-19 patients were retrospectively assessed. Totally 15 patients with COVID-19 were included in this study. Two of them were moderately ill, six were seriously ill and seven were critically ill. The TCZ was used in combination with methylprednisolone in eight patients. Five patients…

Citation impact

1,290
total citations
FWCI
32.02
Percentile
100%
References
8
Citations per year

Authors

6

Topics & keywords

Keywords
  • Tocilizumab
  • Medicine
  • Internal medicine
  • Interleukin 6
  • Cytokine storm
  • Methylprednisolone
  • Coronavirus disease 2019 (COVID-19)
  • Gastroenterology
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.