An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
University of North Carolina at Chapel Hill · Vanderbilt University Medical Center · +2 more institutions
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Abstract
A ribonucleoside analog inhibits SARS-CoV-2 in human airway epithelial cell cultures and SARS-CoV and MERS-CoV in mice.
Citation impact
1,159
total citations
- FWCI
- 25.22
- Percentile
- 100%
- References
- 70
Citations per year
Authors
28- TPTimothy P. SheahanCorresponding
University of North Carolina at Chapel Hill
- ASAmy SimsCorresponding
University of North Carolina at Chapel Hill
- SZShuntai Zhou
University of North Carolina at Chapel Hill
- RLRachel L. Graham
University of North Carolina at Chapel Hill
- AJAndrea J. Pruijssers
Vanderbilt University Medical Center
Topics & keywords
Topics
Keywords
- Virology
- Coronavirus disease 2019 (COVID-19)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Outbreak
- Coronavirus
- Vero cell
- Biology
- 2019-20 coronavirus outbreak
UN Sustainable Development Goals
- Good health and well-being
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