articleCold Spring Harbor ProtocolsApr 1, 2020Closed access

Bradford Assay for Determining Protein Concentration

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Abstract

The Bradford assay is a quick and fairly sensitive method for measuring the concentrations of proteins. It is based on the shift in absorbance maximum of Coomassie Brilliant Blue G-250 dye from 465 to 595 nm following binding to denatured proteins in solution.

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Topics & keywords

Keywords
  • Coomassie Brilliant Blue
  • Absorbance
  • Bradford protein assay
  • Chromatography
  • Chemistry
  • Bicinchoninic acid assay
  • Biochemistry
  • Biology
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