Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection
ETH Zurich · Swiss Federal Laboratories for Materials Science and Technology · +4 more institutions
Abstract
Hybridization temperature and facilitate the accurate discrimination of two similar gene sequences. Our dual-functional LSPR biosensor exhibits a high sensitivity toward the selected SARS-CoV-2 sequences with a lower detection limit down to the concentration of 0.22 pM and allows precise detection of the specific target in a multigene mixture. This study gains insight into the thermoplasmonic enhancement and its applicability in the nucleic acid tests and viral disease diagnosis.
Citation impact
- FWCI
- 22.34
- Percentile
- 100%
- References
- 39
Authors
6- GQGuangyu Qiu
ETH Zurich, Swiss Federal Laboratories for Materials Science and Technology
- ZGZhibo Gai
Shandong University of Traditional Chinese Medicine, University of Zurich, University Hospital of Zurich
- YTYile Tao
ETH Zurich, Swiss Federal Laboratories for Materials Science and Technology
- JSJean Schmitt
ETH Zurich, Swiss Federal Laboratories for Materials Science and Technology
- GAGerd A. Kullak‐Ublick
Novartis (Switzerland), University of Zurich, University Hospital of Zurich
Topics & keywords
- Photothermal therapy
- Biosensor
- Surface plasmon resonance
- Plasmon
- Coronavirus
- Nanotechnology
- Nucleic acid
- Virology
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