ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
St. Paul's Hospital · Providence Health Care · +1 more institution
Indexed incrossrefpubmed
Abstract
Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation.https://bit.ly/3bC29es
Citation impact
859
total citations
- FWCI
- 95.02
- Percentile
- 100%
- References
- 20
Citations per year
Authors
8- JMJanice M. LeungCorresponding
St. Paul's Hospital, Providence Health Care, University of British Columbia
- CXChen Xi Yang
St. Paul's Hospital, University of British Columbia, Providence Health Care
- ARAnthony Raymond Tam
University of British Columbia, Providence Health Care, St. Paul's Hospital
- TSTawimas Shaipanich
University of British Columbia, St. Paul's Hospital, Providence Health Care
- THTillie‐Louise Hackett
University of British Columbia, Providence Health Care, St. Paul's Hospital
Topics & keywords
Topics
Keywords
- Medicine
- COPD
- Coronavirus disease 2019 (COVID-19)
- Airway
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- 2019-20 coronavirus outbreak
- Receptor
- Smoking cessation
UN Sustainable Development Goals
- Good health and well-being
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