articleEuropean Journal of Clinical InvestigationApr 15, 2020Closed access

Systemic immune‐inflammation index (SII) predicted clinical outcome in patients with coronary artery disease

National Yang Ming Chiao Tung University · Taipei Veterans General Hospital · +2 more institutions

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Abstract

Background

This study examines the predictive value of a novel systemic immune-inflammation index (SII, platelet × neutrophil/lymphocyte ratio) in coronary artery disease (CAD) patients.

Methods

A total of 5602 CAD patients who had undergone a percutaneous coronary intervention (PCI) were enrolled. They were divided into two groups by baseline SII score (high SII vs low SII) to analyse the relationship between SII groups and the long-term outcome. The primary outcomes were major cardiovascular events (MACE) which includes nonfatal myocardial infarction (MI), nonfatal stroke and cardiac death. Secondary outcomes included a composite of MACE and hospitalization for congestive heart failure.

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