Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis

Abstract Objective To estimate and compare progression rates to type 2 diabetes mellitus (T2DM) in women with gestational diabetes mellitus (GDM) and healthy controls. Design Systematic review and meta-analysis. Data sources Medline and Embase between January 2000 and December 2019, studies published in English and conducted on humans. Eligibility criteria for selecting studies Observational studies investigating progression to T2DM. Inclusion criteria were postpartum follow-up for at least 12 months, incident physician based diagnosis of diabetes, T2DM reported as a separate outcome rather than combined with impaired fasting glucose or impaired glucose tolerance, and studies with both a group of patients with…

• NI
  National Institute for Health and Care Research
• DO
  Department of Health and Social Care
• MR
  Medical Research Council

  Awards: MR/R020981/1, MR/P013538/1, MR/R020981/2, MR/P013538/2
• NL
  NIHR Leicester Biomedical Research Centre