A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
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Abstract
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we consolidate the recent advances on novel nitrogen-containing heterocycles and their distinct biological activities,…
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1,611
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5Topics & keywords
Topics
Keywords
- Nitrogen
- Drug discovery
- Chemistry
- Combinatorial chemistry
- Nanotechnology
- Organic chemistry
- Materials science
- Biochemistry
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