reviewMoleculesApr 20, 2020GOLD OA

A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

University of KwaZulu-Natal

PubMed
Indexed incrossrefdoajpubmed

Abstract

The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we consolidate the recent advances on novel nitrogen-containing heterocycles and their distinct biological activities,…

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