Human Leukocyte Antigen Susceptibility Map for Severe Acute Respiratory Syndrome Coronavirus 2
Oregon Health & Science University · Portland VA Research Foundation · +1 more institution
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Abstract
Individual genetic variation may help to explain different immune responses to a virus across a population. In particular, understanding how variation in HLA may affect the course of COVID-19 could help identify individuals at higher risk from the disease. HLA typing can be fast and inexpensive. Pairing HLA typing with COVID-19 testing where feasible could improve assessment of severity of viral disease in the population. Following the development of a vaccine against SARS-CoV-2, the virus that causes COVID-19, individuals with high-risk HLA types could be prioritized for vaccination.
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Authors
7Topics & keywords
Topics
Keywords
- Biology
- Virology
- Immunology
- Respiratory system
- Antigen
- Betacoronavirus
- Coronavirus
- Coronavirus disease 2019 (COVID-19)
UN Sustainable Development Goals
- Good health and well-being
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