COVID-19 in solid organ transplant recipients: Initial report from the US epicenter

Solid organ transplant recipients may be at a high risk for SARS-CoV-2 infection and poor associated outcomes. We herein report our initial experience with solid organ transplant recipients with SARS-CoV-2 infection at two centers during the first 3 weeks of the outbreak in New York City. Baseline characteristics, clinical presentation, antiviral and immunosuppressive management were compared between patients with mild/moderate and severe disease (defined as ICU admission, intubation or death). Ninety patients were analyzed with a median age of 57 years. Forty-six were kidney recipients, 17 lung, 13 liver, 9 heart, and 5 dual-organ transplants. The most common presenting symptoms were fever (70%), cough (59%),…

• NI
  National Institute of Diabetes and Digestive and Kidney Diseases

  Awards: R01 DK114893, R01 DK114893 and U01 DK116066, DK114893, DK116066, U01 DK116066
• NC
  National Center for Advancing Translational Sciences

  Awards: KL2 TR001874, U01 DK116066, TR001874
• NI
  National Institute on Minority Health and Health Disparities

  Awards: R01 DK114893, R01 MD14161, U01 DK116066